Wieland Kiess Selected Research

Lipoma (Lipomata)

12/2020	A new human adipocyte model with PTEN haploinsufficiency.
10/2019	The Novel Phosphatidylinositol-3-Kinase (PI3K) Inhibitor Alpelisib Effectively Inhibits Growth of PTEN-Haploinsufficient Lipoma Cells.
6/2018	Simvastatin induces apoptosis in PTEN‑haploinsufficient lipoma cells.
1/2016	Resveratrol Potentiates Growth Inhibitory Effects of Rapamycin in PTEN-deficient Lipoma Cells by Suppressing p70S6 Kinase Activity.
6/2015	Phosphatidylinositol 3-kinase (PI3K) signalling regulates insulin-like-growth factor binding protein-2 (IGFBP-2) production in human adipocytes.
4/2014	Sirolimus treatment of severe PTEN hamartoma tumor syndrome: case report and in vitro studies.

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Wieland Kiess Research Topics

Disease

59	Obesity 02/2022 - 09/2003
21	Insulin Resistance 11/2019 - 08/2004
20	Neoplasms (Cancer) 01/2022 - 12/2005
14	Overweight 12/2021 - 02/2009
13	Type 2 Diabetes Mellitus (MODY) 02/2022 - 08/2004
11	Inflammation (Inflammations) 01/2020 - 06/2005
11	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2019 - 06/2002
7	Body Weight (Weight, Body) 12/2020 - 05/2006
7	Pediatric Obesity 01/2019 - 08/2004
6	Dyslipidemias (Dyslipidemia) 01/2021 - 01/2006
6	Lipoma (Lipomata) 12/2020 - 04/2014
6	Metabolic Syndrome (Dysmetabolic Syndrome X) 11/2019 - 08/2004
5	Weight Gain 01/2022 - 03/2002
5	Drug-Related Side Effects and Adverse Reactions 01/2022 - 01/2014
5	Non-alcoholic Fatty Liver Disease 12/2021 - 09/2015
5	Phenylketonurias (Phenylketonuria) 05/2021 - 07/2002
5	Cardiovascular Diseases (Cardiovascular Disease) 11/2016 - 12/2005
4	Metabolic Diseases (Metabolic Disease) 05/2021 - 06/2007
4	Thyroid Diseases (Thyroid Disease) 02/2021 - 01/2014
4	Glucose Intolerance 01/2021 - 01/2012
3	Hypersensitivity (Allergy) 03/2022 - 11/2015
3	Asthma (Bronchial Asthma) 03/2022 - 01/2018
3	Hypertrophy 01/2022 - 04/2015
3	Birth Weight (Birth Weights) 01/2022 - 03/2002
3	Growth Disorders 02/2021 - 05/2010
3	Hypertension (High Blood Pressure) 01/2019 - 01/2006
3	Epilepsy (Aura) 01/2018 - 01/2016
3	Cystic Fibrosis (Mucoviscidosis) 08/2017 - 11/2004
3	Multiple Hamartoma Syndrome (Cowden's Disease) 01/2017 - 04/2014
2	Bone Resorption 12/2021 - 01/2020
2	Morbid Obesity 01/2021 - 05/2017
2	Simpson-Golabi-Behmel syndrome 12/2020 - 01/2011
2	Apnea 07/2020 - 08/2007
2	Weight Loss (Weight Reduction) 07/2020 - 12/2004
2	Hepatocellular Carcinoma (Hepatoma) 08/2019 - 03/2015
2	Disease Progression 12/2018 - 06/2013
2	Diabetes Mellitus 01/2018 - 02/2014
2	Hyperphagia (Overeating) 01/2017 - 01/2017
2	Infections 04/2016 - 01/2002
2	Lipomatosis 01/2016 - 04/2014

Drug/Important Bio-Agent (IBA)

23	Glucose (Dextrose)FDA LinkGeneric 08/2022 - 12/2004
22	Insulin (Novolin)FDA Link 01/2021 - 03/2005
13	LeptinIBA 01/2021 - 03/2002
12	LipidsIBA 01/2021 - 09/2003
11	AdipokinesIBA 02/2022 - 08/2004
11	Nicotinamide PhosphoribosyltransferaseIBA 09/2018 - 06/2007
10	AdiponectinIBA 01/2018 - 08/2004
9	Hormones (Hormone)IBA 06/2022 - 03/2002
8	Triglycerides (Triacylglycerol)IBA 01/2021 - 09/2003
8	NAD (NADH)IBA 01/2019 - 01/2009
7	Growth Hormone (Somatotropin)IBA 01/2019 - 01/2004
6	Insulin-Like Growth Factor I (IGF-1)IBA 01/2022 - 03/2002
6	Biomarkers (Surrogate Marker)IBA 12/2021 - 03/2007
6	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2021 - 04/2014
6	TensinsIBA 01/2021 - 04/2014
5	EnzymesIBA 08/2022 - 01/2015
5	Proteins (Proteins, Gene)FDA Link 01/2021 - 11/2003
5	Anticonvulsants (Antiepileptic Drugs)IBA 09/2020 - 01/2014
5	CytokinesIBA 01/2020 - 06/2005
4	Sirolimus (Rapamycin)FDA Link 01/2022 - 04/2014
4	Biological ProductsIBA 09/2021 - 09/2003
4	Uric Acid (Urate)IBA 10/2019 - 08/2004
4	CholesterolIBA 03/2017 - 09/2003
4	HDL CholesterolIBA 07/2016 - 01/2012
4	LDL CholesterolIBA 07/2016 - 01/2012
4	Messenger RNA (mRNA)IBA 01/2011 - 11/2003
3	hydroxide ionIBA 01/2022 - 01/2018
3	C-Reactive ProteinIBA 01/2022 - 12/2007
3	Pharmaceutical PreparationsIBA 01/2022 - 01/2015
3	Vitamin D FDA LinkGeneric 12/2021 - 04/2016
3	Transaminases (Aminotransferases)IBA 12/2021 - 08/2013
3	Blood Glucose (Blood Sugar)IBA 01/2019 - 01/2011
3	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2019 - 10/2004
3	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 01/2018 - 09/2017
3	oxidized low density lipoproteinIBA 07/2016 - 03/2005
3	Phenylalanine (L-Phenylalanine)FDA Link 09/2015 - 07/2002
2	Gonadal Steroid Hormones (Sex Hormones)IBA 06/2022 - 11/2019
2	Testosterone (Sustanon)FDA Link 06/2022 - 11/2019
2	AntigensIBA 01/2022 - 04/2010
2	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2022 - 01/2017
2	Calcitonin (Calcitonin, Eel)FDA LinkGeneric 12/2021 - 01/2019
2	Alkaline PhosphataseIBA 12/2021 - 01/2019
2	OsteocalcinIBA 12/2021 - 01/2020
2	CalciumIBA 12/2021 - 01/2020
2	glutamyl- lysyl- alanyl- histidyl- aspartyl- glycyl- glycyl- arginineIBA 12/2021 - 01/2020
2	Human Growth Hormone (Saizen)FDA LinkGeneric 01/2020 - 01/2015
2	Immunoglobulin E (IgE)IBA 01/2020 - 11/2015
2	Immunoglobulin A (IgA)IBA 01/2020 - 01/2002
2	Sirtuin 1IBA 08/2019 - 01/2009
2	Phosphotransferases (Kinase)IBA 08/2019 - 01/2016
2	Prednisone (Sone)FDA LinkGeneric 12/2018 - 11/2004
2	AutoantibodiesIBA 01/2018 - 10/2015
2	TransferasesIBA 01/2017 - 05/2011
2	ResveratrolIBA 01/2016 - 01/2014

Therapy/Procedure

17	Therapeutics 05/2021 - 01/2004
3	Drug Therapy (Chemotherapy) 01/2020 - 11/2004
2	Bariatric Surgery 01/2021 - 07/2020
2	Oral Hygiene (Dental Hygiene) 05/2019 - 01/2018
2	Radiotherapy 01/2019 - 01/2018
2	Glycemic Control 09/2017 - 10/2004